Criteria of convalescent plasma donor that affects COVID-19 antibody titer at UDD PMI Tangerang City in 2021
Main Article Content
Keywords
Convalescent plasma, antibody titer, COVID-19, donor, clinical history/symptoms, age, gender
Abstract
Introduction: Since the start of the COVID-19 pandemic, the use of convalescent plasma has been an approach being researched to treat this infection. Convalescent plasma contains antibodies produced by individuals who have recovered from COVID-19, and high levels of antibody titers are thought to be more effective in providing protection against infection. The data analyzed included the number of donors who passed, history/symptoms of COVID-19 infection, age , sex, and antibody titer results. This research will provide an understanding of the characteristics of an effective convalescent plasma donor, appropriate selection criteria, and expected antibody titer levels. The results of this study are expected to increase the effectiveness of using convalescent plasma in treating COVID-19 patients at PMI Tangerang City, as well as assist in efforts to control the spread of the virus more efficiently. This study aimed to analyze the criteria for convalescent plasma donors influencing COVID-19 antibody titers at UDD PMI Tangerang City in 2021.
Methods: This research was conducted at UDD PMI Tangerang City using a descriptive observational method. Data will be collected retrospectively from UDD PMI Tangerang City in 2021 to analyze the criteria for convalescent plasma donors and their effect on COVID-19 antibody titers.
Result: The results showed that the donor's clinical history/symptoms, age, and gender had an effect on the COVID-19 antibody titer. Donors with a history/severe clinical symptom (92%) tended to have higher antibody titers. In addition, the age group ≤18 years (74%) and 18-24 years (82%) and male donors (76%) tended to have higher levels of antibody titers.
Conclusion: The findings of this study indicate that criteria for convalescent plasma donors, such as clinical history/symptoms, age, and gender, can affect the antibody titer of COVID-19. Donors with a history/severe clinical symptoms, young age , and men tend to have higher antibody titers. This information can be used to increase the effectiveness of convalescent plasma therapy in treating COVID-19 patients.
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